Max-Joint ® contains Glucosamine Potassium to be consumed by hypertensive patients.

Glucosamine is a natural substance that our body produces and with the overall growth of the organism decreases.

Glucosamine plays an essential role in the formation and repair of cartilage, it is beneficial in the treatment of osteoarthritis and has shown to be effective rehabilitating the cartilage and to repair joints that have been damaged by osteoarthritis. Its efficacy for the treatment of osteoarthritis has been demonstrated through many studies.

The chondro-protective effect and anti-evolutionary  of Max-Joint ® added to its symptomatic action, modifies the development of osteoarthritis and significantly relieves pain at rest and during movement, improving mobility.

COMPONENTS

This comprehensive formula of the Max-Joint ® is associated chondroitin sulfate, another natural substance, to complement the action of Glucosamine and improve the action of protection and cartilage regeneration. Chondroitin helps to eliminate the very causes of inflammation by inhibiting enzymes that degrade cartilage and promotes quality of synovial fluid helping to absorb the impact on joints while Glucosamine increases the viscosity of synovial fluid, providing the necessary lubrication. In addition, chondroitin promotes the regeneration process of cartilage and inflammation thus helping the reconstruction of healthier joints.

Max-Joint ® has also incorporated a form of sulfur that is found naturally in human body which stimulates healthy connective tissues such as tendons, ligaments and muscles and it is so important for conditions such as arthritis, muscle aches, bursitis, etc .*experiments have shown that the sulfur contained in the methylsulfonylmethane (MSM) helps the formation of essential amino acids methionine and cysteine. These amino acids are most involved in the reconstruction of cartilage. One of the most important applications of organic sulfur, MSM is its demonstrated ability to relieve pain associated with systemic inflammatory diseases.
People with arthritis report substantial and lasting relief.
Max-Joint ® also includes three other important ingredients. The natural vitamin C ascalcium ascorbate, which provides higher levels of vitamin C in the blood that would bring an equal amount of ascorbic acid. Vitamin C is a powerful antioxidant essential, which can protect joints from damage done by free radicals, causing inflammation in the joints. Recent research is showing that vitamin C may help to prevent loss of bone  and  cartilage  disorders  associated  with aging. Vitamin C plays a key role in the formation of collagen, a protein that is the main constituent of tendons and which enhances the body’s ability to repair damaged cartilage.

The chondro-protective effect and anti-evolutionary  of Max-Joint ® added to its symptomatic action, modifies the development of osteoarthritis and significantly relieves pain at rest and during movement, improving mobility.
Glucosamine has been classified by the International League Against  Rheumatism (ILAR) as a symptomatic slow-acting drug for osteoarthrosis  (SYSADOA), and also for its therapeutic action has been classified as disease (anti-evolutionary) modifying drug of of osteoarthrosis (DMOAD).
Max-Joint ® is also indicated for the treatment of primary and secondary  arthrosis, osteochondrosis, spondylosis, chondromalacia of the kneecap  scapulohumeral periarthritis, prevention of arthrosis in people with risk factors  such as age over 45 years, obesity, persons who  practice high-impact  sports for the joints, patients with a history of repeated injuries and / or fractures that have affected joints.
Some of the many potential benefits of taking Max-Joint ® are:
• Offers the possibility of benefit to maintain healthy joints.
• Maximize the production of liquids of lubrication of the joint.
• Improve and maintain mobility and maximum flexibility in the joints.
• Maintains strength of tissues.
• Increases anabolism and growth of tissues. (anabolic)
• Reduces tissue damage. (anti-catabolic)
• Allows a better recovery from injury.
• Improved physical performance.
• Reduces noise generated by rubbing the joints.
• inhibits the degradation of connective tissue. 
• Stabilizes the breadth of space between the joints.
• Enhances synthesis of connective tissues.
• Decreases tissue degradation.
• Increases bone mass and other tissues healing them and repairing them.
• Reduces skin wrinkles and expression lines
• Helps to maintain strong muscles, bones and connective tissues.
• Helps reduce exercise-related injuries.
• Improves hydration of all tissues.
• Maintains a good connective tissue to cushion and absorb shock.
• Provides strength and stability to joints.
• Contributes to maintain healthy skin, hair and nails.
• helps to relieve minor or temporary pain associated with daily activities
• Regenerate cartilage and synovial fluid keeping joints strong and flexible
• Helps to reduce bone loss associated with arthritis
• No adverse collateral effects.
In addition to the benefits that Max-Joint ® presents for the joints, bones and muscles, many people also experience improvement in their hair, nails and skin, because these structures contain high amounts of connective tissue.

• PHARMACOLOGICAL ACTION OF MAX JOINT

The mechanism of action of the formula Max-Joint ® can be explained by three effects:

Anabolic effect
• These substances constitute essential substrate for the biosynthesis of        proteoglycans by chondrocytes
• stimulate proteoglycan synthesis
• Promote the production of hyaluronate in synovial fluid
Anti-catabolic effect
• They inhibit the action of catabolic enzymes (metalloproteinases) such asstromelysin, collagenase, phospholipase A2 and gelatinase.
• promote the adhesion of chondrocytes to fibronectin.
Anti-inflammatory effects
• They inhibit superoxide radical generation.
• They inhibit the activity of lysosomal enzymes.
• inhibit the inducible nitric oxide synthesis.
• Increase the production of protein kinase C (PKC).

• PRECAUTIONS

As an element in the body naturally, Max-Joint ® requires no special precautions  or measures given the nature of it. The administration in diabetic patients, requires  monitoring of plasma glucose levels.

• RESTRICTIONS OF USE DURING PREGNANCY AND LACTATION

In animal model studies occurred no adverse effects on fetal development or during lactation. Administration of the product in humans under these conditions (pregnancy and lactation), should be limited to cases of necessity and physician’s assessment provided under their supervision and discretion.

• ADVERSE REACTIONS

Eventually, gastrointestinal disturbances.

• DOSAGE AND ADMINISTRATION

Max-Joint ® Capsules is administered orally 1 capsule 3 times per day (breakfast, lunch and dinner). This dosing schedule reduces  symptoms  significantly, also improving joint mobility. The length of the initial therapy is between 4 and 6 weeks.